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BMP signaling agonist sb4

CAS No. 100874-08-6

BMP signaling agonist sb4( SB 4 | SB4 | SB-4 )

Catalog No. M10057 CAS No. 100874-08-6

BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 35 Get Quote
10MG 50 Get Quote
25MG 81 Get Quote
50MG 115 Get Quote
100MG 177 Get Quote
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Biological Information

  • Product Name
    BMP signaling agonist sb4
  • Note
    Research use only, not for human use.
  • Brief Description
    BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM.
  • Description
    BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes; increases the phosphorylation of key second messengers (SMADs-1/5/9) and also increased expression of direct target genes (inhibitors of DNA binding, ID1 and ID3) in canonical BMP signaling.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SB 4 | SB4 | SB-4
  • Pathway
    TGF-beta/Smad
  • Target
    TGFBR
  • Recptor
    TGFBR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    100874-08-6
  • Formula Weight
    320.204
  • Molecular Formula
    C14H10BrNOS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (312.30 mM)
  • SMILES
    BrC1=CC=C(CSC2=NC3=CC=CC=C3O2)C=C1
  • Chemical Name
    2-((4-bromobenzyl)thio)benzo[d]oxazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bradford STJ, et al. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006817.
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